Ontology highlight
ABSTRACT:
SUBMITTER: Shapiro M
PROVIDER: S-EPMC2515170 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Shapiro M M Duca K A KA Lee K K Delgado-Eckert E E Hawkins J J Jarrah A S AS Laubenbacher R R Polys N F NF Hadinoto V V Thorley-Lawson D A DA
Journal of theoretical biology 20080216 4
Epstein-Barr virus (EBV) is an important human pathogen that establishes a life-long persistent infection and for which no precise animal model exists. In this paper, we describe in detail an agent-based model and computer simulation of EBV infection. Agents representing EBV and sets of B and T lymphocytes move and interact on a three-dimensional grid approximating Waldeyer's ring, together with abstract compartments for lymph and blood. The simulation allows us to explore the development and re ...[more]