Molecular cytogenetic evidence of rearrangements on the Y chromosome of the threespine stickleback fish.

ABSTRACT: To identify the processes shaping vertebrate sex chromosomes during the early stages of their evolution, it is necessary to study systems in which genetic sex determination was recently acquired. Previous cytogenetic studies suggested that threespine stickleback fish (Gasterosteus aculeatus) do not have a heteromorphic sex chromosome pair, although recent genetic studies found evidence of an XY genetic sex-determination system. Using fluorescence in situ hybridization (FISH), we report that the threespine stickleback Y chromosome is heteromorphic and has suffered both inversions and deletion. Using the FISH data, we reconstruct the rearrangements that have led to the current physical state of the threespine stickleback Y chromosome. These data demonstrate that the threespine Y is more dege

SUBMITTER: Ross JA 

PROVIDER: S-EPMC2516089 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature