Effects of colonization, luminescence, and autoinducer on host transcription during development of the squid-vibrio association.

ABSTRACT: The light-organ symbiosis between the squid Euprymna scolopes and the luminous bacterium Vibrio fischeri offers the opportunity to decipher the hour-by-hour events that occur during the natural colonization of an animal's epithelial surface by its microbial partners. To determine the genetic basis of these events, a glass-slide microarray was used to characterize the light-organ transcriptome of juvenile squid in response to the initiation of symbiosis. Patterns of gene expression were compared between animals not exposed to the symbiont, exposed to the wild-type symbiont, or exposed to a mutant symbiont defective in either of two key characters of this association: bacterial luminescence or autoinducer (AI) production. Hundreds of genes were differentially regulated as a result of symbios

SUBMITTER: Chun CK 

PROVIDER: S-EPMC2516268 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature