A new construction of 2-alkoxypyrans by an acylation-reductive cyclization sequence.

ABSTRACT: A new convergent synthetic approach to a pyran motif common to many naturally occurring structures is described. In this approach, two fragments are joined by esterification, and a subsequent intramolecular reductive cyclization affords the 2-hydroxypyran.

SUBMITTER: Heumann LV 

PROVIDER: S-EPMC2516373 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature