Synthetic studies toward the bryostatins: a substrate-controlled approach to the A-ring.

ABSTRACT: [reaction: see text] The synthesis of a C1-C13 A-ring subunit of bryostatin 1 is detailed. The key features of the approach include the convergent fragment assembly with a highly stereoselective construction of the C7-C8 bond indicated above.

SUBMITTER: Keck GE 

PROVIDER: S-EPMC2516405 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature