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Association between 16S-23S internal transcribed spacer sequence groups of Mycobacterium avium complex and pulmonary disease.


ABSTRACT: Organisms within the Mycobacterium avium complex (MAC) may have differential virulence. We compared 33 subjects with MAC pulmonary disease to 75 subjects with a single positive culture without disease. M. avium isolates were significantly more likely to be associated with MAC pulmonary disease (odds ratio = 5.14, 95% confidence interval = 1.25 to 22.73) than M. intracellulare.

SUBMITTER: Stout JE 

PROVIDER: S-EPMC2519484 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature

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Association between 16S-23S internal transcribed spacer sequence groups of Mycobacterium avium complex and pulmonary disease.

Stout Jason E JE   Hopkins Gregory W GW   McDonald Jay R JR   Quinn Anita A   Hamilton Carol D CD   Reller L Barth LB   Frothingham Richard R  

Journal of clinical microbiology 20080611 8


Organisms within the Mycobacterium avium complex (MAC) may have differential virulence. We compared 33 subjects with MAC pulmonary disease to 75 subjects with a single positive culture without disease. M. avium isolates were significantly more likely to be associated with MAC pulmonary disease (odds ratio = 5.14, 95% confidence interval = 1.25 to 22.73) than M. intracellulare. ...[more]

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