Enantioselective total synthesis of (+)-gliocladin C.

ABSTRACT: The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product. [reaction: see text].

SUBMITTER: Overman LE 

PROVIDER: S-EPMC2526118 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature