The earliest settlers' antiquity and evolutionary history of Indian populations: evidence from M2 mtDNA lineage.

ABSTRACT:

Background

The "out of Africa" model postulating single "southern route" dispersal posits arrival of "Anatomically Modern Human" to Indian subcontinent around 66-70 thousand years before present (kyBP). However the contributions and legacy of these earliest settlers in contemporary Indian populations, owing to the complex past population dynamics and later migrations has been an issue of controversy. The high frequency of mitochondrial lineage "M2" consistent with its greater age and distribution suggests that it may represent the phylogenetic signature of earliest settlers. Accordingly, we attempted to re-evaluate the impact and contribution of earliest settlers in shaping the genetic diversity and structure of contemporary Indian populations; using our newly sequenced 72 and 4 pu

SUBMITTER: Kumar S 

PROVIDER: S-EPMC2528015 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature