Synthesis of functionalized organotrifluoroborates via halomethyltrifluoroborates.

ABSTRACT: [reaction: see text] Potassium bromo- and iodomethyltrifluoroborates have been prepared via in situ reaction of n-BuLi with dibromo- and diiodomethane, respectively, in the presence of trialkyl borates, followed by treatment with KHF(2). Moreover, a new synthetic method for the preparation of potassium organotrifluoroborates through nucleophilic substitution of the halide in these potassium halomethyltrifluoroborates is described.

SUBMITTER: Molander GA 

PROVIDER: S-EPMC2528247 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature