Assessing the feasibility of GS FLX Pyrosequencing for sequencing the Atlantic salmon genome.

ABSTRACT:

Background

With a whole genome duplication event and wealth of biological data, salmonids are excellent model organisms for studying evolutionary processes, fates of duplicated genes and genetic and physiological processes associated with complex behavioral phenotypes. It is surprising therefore, that no salmonid genome has been sequenced. Atlantic salmon (Salmo salar) is a good representative salmonid for sequencing given its importance in aquaculture and the genomic resources available. However, the size and complexity of the genome combined with the lack of a sequenced reference genome from a closely related fish makes assembly challenging. Given the cost and time limitations of Sanger sequencing as well as recent improvements to next generation sequencing technologies, we exami

SUBMITTER: Quinn NL 

PROVIDER: S-EPMC2532694 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature