Organocatalytic enantioselective synthesis of alpha-hydroxy phosphonates.

ABSTRACT: Tertiary alpha-hydroxy phosphonates have been synthesized in good yields and high enantiomeric purity (up to 99% ee) through a novel l-proline-catalyzed cross aldol reaction of alpha-keto phosphonates and ketones.

SUBMITTER: Samanta S 

PROVIDER: S-EPMC2535926 | biostudies-literature | 2006 Jun

REPOSITORIES: biostudies-literature