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Formal syntheses of (+/-)-pinnaic acid and (+/-)-halichlorine.


ABSTRACT: [chemical reaction: see text]. Concise formal syntheses of marine alkaloids (+/-)-pinnaic acid (1) and (+/-)-halichlorine (2) have been accomplished from a common intermediate. The syntheses illustrate the utility of selective olefin cross metathesis methodologies for the elaboration of advanced synthetic intermediates in complex molecule synthesis.

SUBMITTER: Andrade RB 

PROVIDER: S-EPMC2536714 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature