Changes in arterial oxygenation and self-reported oxygen use after lung volume reduction surgery.

ABSTRACT:

Rationale

Lung volume reduction surgery (LVRS) is inconsistently reported to improve arterial oxygenation in patients with chronic obstructive pulmonary disease.

Objectives

We studied the effects of surgery on oxygenation in a large cohort and identified predictors of postoperative oxygenation improvement.

Methods

We evaluated oxygenation in 1,078 subjects with chronic obstructive pulmonary disease enrolled in the National Emphysema Treatment Trial after LVRS compared with medical control subjects, including arterial blood gases, use of supplemental oxygen during treadmill walking, and self-reported use of oxygen during rest, exertion, and sleep.

Measurements and main results

Pa(O(2)) breathing room air was equal in medical and surgical subjects at baseline (64

SUBMITTER: Snyder ML 

PROVIDER: S-EPMC2542439 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature