Evaluation of three real-time PCR assays for detection of Mycoplasma pneumoniae in an outbreak investigation.

ABSTRACT: We compared the performances of three recently optimized real-time PCR assays derived from distinct genomic regions of Mycoplasma pneumoniae during an outbreak. Comprehensive evaluation established that a newly described toxin gene represents a superior target for detecting M. pneumoniae DNA in clinical specimens, although use of multiple targets may increase testing confidence.

SUBMITTER: Winchell JM 

PROVIDER: S-EPMC2546712 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature