Genomic analysis of the role of RNase R in the turnover of Pseudomonas putida mRNAs.

ABSTRACT: RNase R is a 3'-5' highly processive exoribonuclease that can digest RNAs with extensive secondary structure. We analyzed the global effect of eliminating RNase R on the Pseudomonas putida transcriptome and the expression of the rnr gene under diverse conditions. The absence of RNase R led to increased levels of many mRNAs, indicating that it plays an important role in mRNA turnover.

SUBMITTER: Fonseca P 

PROVIDER: S-EPMC2546782 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature