Consolidated strategy for the analysis of microarray spike-in data.

ABSTRACT: As the number of users of microarray technology continues to grow, so does the importance of platform assessments and comparisons. Spike-in experiments have been successfully used for internal technology assessments by microarray manufacturers and for comparisons of competing data analysis approaches. The microarray literature is saturated with statistical assessments based on spike-in experiment data. Unfortunately, the statistical assessments vary widely and are applicable only in specific cases. This has introduced confusion into the debate over best practices with regards to which platform, protocols and data analysis tools are best. Furthermore, cross-platform comparisons have proven difficult because reported concentrations are not comparable. In this article, we introduce two new sp

SUBMITTER: McCall MN 

PROVIDER: S-EPMC2553586 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature