Post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillation.

ABSTRACT:

Objective

We have observed consistent hemodynamic patterns after restoration of spontaneous circulation (ROSC) after ventricular fibrillation (VF) cardiac arrest. We sought to characterize the time-course of these patterns, and to determine whether these differed based on duration of the VF insult.

Methods

We performed a retrospective review of data from a randomized animal experiment that was conducted in an AAALAC-approved animal laboratory. We used mixed-breed domestic swine of either sex. Animals were anesthetized and instrumented for continuous recording of ECG and blood pressures. VF was induced electrically and allowed to progress for various times ranging from brief (22s) to moderate (less than 3 min) to prolonged (3-10 min). All animals were initially shocked (150J)

SUBMITTER: Menegazzi JJ 

PROVIDER: S-EPMC2556071 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature