Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions.

ABSTRACT: Monofunctionalized polyamide-based dendrimers containing either a terminal azide or alkyne moiety have been designed and synthesized via a convergent synthetic approach. The monofunctionalization allows for the single attachment of a functional moiety in quantitative yields by using 1,3-dipolar cycloadditions, thereby opening the possibility for targeted dendrimer functionalization.

SUBMITTER: Yoon K 

PROVIDER: S-EPMC2559814 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature