Ontology highlight
ABSTRACT:
SUBMITTER: King N
PROVIDER: S-EPMC2562698 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Nature 20080201 7180
Choanoflagellates are the closest known relatives of metazoans. To discover potential molecular mechanisms underlying the evolution of metazoan multicellularity, we sequenced and analysed the genome of the unicellular choanoflagellate Monosiga brevicollis. The genome contains approximately 9,200 intron-rich genes, including a number that encode cell adhesion and signalling protein domains that are otherwise restricted to metazoans. Here we show that the physical linkages among protein domains of ...[more]