Origin of structural difference in metabolic networks with respect to temperature.

ABSTRACT:

Background

Metabolism is believed to adaptively shape-shift with changing environment. In recent years, a structural difference with respect to temperature, which is an environmental factor, has been revealed in metabolic networks, implying that metabolic networks transit with temperature. Subsequently, elucidatation of the origin of these structural differences due to temperature is important for understanding the evolution of life. However, the origin has yet to be clarified due to the complexity of metabolic networks.

Results

Consequently, we propose a simple model with a few parameters to explain the transitions. We first present mathematical solutions of this model using mean-field approximation, and demonstrate that this model can reproduce structural properties, such

SUBMITTER: Takemoto K 

PROVIDER: S-EPMC2564917 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature