Population structure analysis of the Mycobacterium tuberculosis Beijing family indicates an association between certain sublineages and multidrug resistance.

ABSTRACT: Our population-based study of the Mycobacterium tuberculosis Beijing family examined the frequency of occurrence of each sublineage of this family, classified by using 10 synonymous single-nucleotide polymorphisms. The results revealed the overabundance of two evolutionary sublineages in a population of multidrug-resistant and extensively drug-resistant tuberculosis bacteria.

SUBMITTER: Iwamoto T 

PROVIDER: S-EPMC2565899 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature