The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium.

ABSTRACT: CorA is the primary Mg(2+) channel in Salmonella enterica serovar Typhimurium. A corA mutant is attenuated in mice and defective for invasion of and replication within epithelial cells. Microarray studies show that several virulence effectors are repressed in a corA mutant strain, which ultimately manifests itself as a decrease in virulence.

SUBMITTER: Papp-Wallace KM 

PROVIDER: S-EPMC2566004 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature