Gene expression profiling of two distinct neuronal populations in the rodent spinal cord.

ABSTRACT:

Background

In the field of neuroscience microarray gene expression profiles on anatomically defined brain structures are being used increasingly to study both normal brain functions as well as pathological states. Fluorescent tracing techniques in brain tissue that identifies distinct neuronal populations can in combination with global gene expression profiling potentially increase the resolution and specificity of such studies to shed new light on neuronal functions at the cellular level.

Methodology/principal findings

We examine the microarray gene expression profiles of two distinct neuronal populations in the spinal cord of the neonatal rat, the principal motor neurons and specific interneurons involved in motor control. The gene expression profiles of the respective cel

SUBMITTER: Ryge J 

PROVIDER: S-EPMC2566599 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature