Direct identification of the Meloidogyne incognita secretome reveals proteins with host cell reprogramming potential.

ABSTRACT: The root knot nematode, Meloidogyne incognita, is an obligate parasite that causes significant damage to a broad range of host plants. Infection is associated with secretion of proteins surrounded by proliferating cells. Many parasites are known to secrete effectors that interfere with plant innate immunity, enabling infection to occur; they can also release pathogen-associated molecular patterns (PAMPs, e.g., flagellin) that trigger basal immunity through the nematode stylet into the plant cell. This leads to suppression of innate immunity and reprogramming of plant cells to form a feeding structure containing multinucleate giant cells. Effectors have generally been discovered using genetics or bioinformatics, but M. incognita is non-sexual and its genome sequence has not yet been reporte

SUBMITTER: Bellafiore S 

PROVIDER: S-EPMC2568823 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature