Molecular characterization of highly pathogenic H5N1 avian influenza viruses isolated in Sweden in 2006.

ABSTRACT:

Background

The analysis of the nonstructural (NS) gene of the highly pathogenic (HP) H5N1 avian influenza viruses (AIV) isolated in Sweden early 2006 indicated the co-circulation of two sub-lineages of these viruses at that time. In order to complete the information on their genetic features and relation to other HP H5N1 AIVs the seven additional genes of twelve Swedish isolates were amplified in full length, sequenced, and characterized.

Results

The presence of two sub-lineages of HP H5N1 AIVs in Sweden in 2006 was further confirmed by the phylogenetic analysis of approximately the 95% of the genome of twelve isolates that were selected on the base of differences in geographic location, timing and animal species of origin. Ten of the analyzed viruses belonged to sub-clade 2

SUBMITTER: Kiss I 

PROVIDER: S-EPMC2569034 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature