Procedure for recording the simultaneous activity of single neurons distributed across cortical areas during sensory discrimination.

ABSTRACT: We report a procedure for recording the simultaneous activity of single neurons distributed across five cortical areas in behaving monkeys. The procedure consists of a commercially available microdrive adapted to a commercially available neural data collection system. The critical advantage of this procedure is that, in each cortical area, a configuration of seven microelectrodes spaced 250-500 mum can be inserted transdurally and each can be moved independently in the z axis. For each microelectrode, the data collection system can record the activity of up to five neurons together with the local field potential (LFP). With this procedure, we normally monitor the simultaneous activity of 70-100 neurons while trained monkeys discriminate the difference in frequency between two vibrotactile

SUBMITTER: Hernandez A 

PROVIDER: S-EPMC2571910 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature