Intensity of renal support in critically ill patients with acute kidney injury.

ABSTRACT:

Background

The optimal intensity of renal-replacement therapy in critically ill patients with acute kidney injury is controversial.

Methods

We randomly assigned critically ill patients with acute kidney injury and failure of at least one nonrenal organ or sepsis to receive intensive or less intensive renal-replacement therapy. The primary end point was death from any cause by day 60. In both study groups, hemodynamically stable patients underwent intermittent hemodialysis, and hemodynamically unstable patients underwent continuous venovenous hemodiafiltration or sustained low-efficiency dialysis. Patients receiving the intensive treatment strategy underwent intermittent hemodialysis and sustained low-efficiency dialysis six times per week and continuous venovenous hemodiafil

SUBMITTER: VA/NIH Acute Renal Failure Trial Network 

PROVIDER: S-EPMC2574780 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature