Failure to replicate two mate preference QTLs across multiple strains of Drosophila pseudoobscura.

ABSTRACT: Behavioral genetic mapping studies in model organisms predominantly use crosses originating from a single pair of inbred lines to determine the location of alleles that confer genetic variation in the trait of interest, and they often make sweeping generalizations about the genetic architecture of the trait based on these results. A previous study fine mapped mate preference variation between one pair of Drosophila pseudoobscura lines and identified 2 strong-effect behavioral quantitative trait loci (QTLs). Here, we replicated the previous study's mapping design to examine the extent of variation at these behavioral QTLs across 6 pairs of lines, but we were unable to detect effects of either QTL region in the pairs of lines studied. We suggest that the low-discrimination alleles at these 2

SUBMITTER: Barnwell CV 

PROVIDER: S-EPMC2574947 | biostudies-literature | 2008 Nov-Dec

REPOSITORIES: biostudies-literature