Meta-analysis of genome-wide expression patterns associated with behavioral maturation in honey bees.

ABSTRACT:

Background

The information from multiple microarray experiments can be integrated in an objective manner via meta-analysis. However, multiple meta-analysis approaches are available and their relative strengths have not been directly compared using experimental data in the context of different gene expression scenarios and studies with different degrees of relationship. This study investigates the complementary advantages of meta-analysis approaches to integrate information across studies, and further mine the transcriptome for genes that are associated with complex processes such as behavioral maturation in honey bees. Behavioral maturation and division of labor in honey bees are related to changes in the expression of hundreds of genes in the brain. The information from various mi

SUBMITTER: Adams HA 

PROVIDER: S-EPMC2582039 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature