Virulence potential of Staphylococcus aureus strains isolated from diabetic foot ulcers: a new paradigm.

ABSTRACT:

Objective

The purpose of this study was to assess the virulence potential of Staphylococcus aureus strains isolated from diabetic foot ulcers and to discriminate noninfected from infected ulcers.

Research design and methods

Diabetic patients hospitalized in a diabetic foot department with a foot ulcer were prospectively enrolled if they had been free of antibiotic treatment over the previous 6 months. At admission, ulcers were classified as infected or noninfected on the basis of clinical examination, according to the International Working Group on the Diabetic Foot system. Only patients carrying S. aureus as the sole pathogen were included. In individuals with a grade 1 ulcer, a second bacterial specimen was obtained 1 month later. Using virulence genotyping markers, clonal

SUBMITTER: Sotto A 

PROVIDER: S-EPMC2584189 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature