A new method for the synthesis of H(4)-BINOL.

ABSTRACT: A method amenable to the gram scale synthesis of (R)-H 4-BINOL, a derivative of (R)-BINOL and ligand of interest in asymmetric catalysis, is described. The key step is the net partial hydrogenation of (R)-BINOL made possible by prior bis-etherification of the parent BINOL.

SUBMITTER: Heumann LV 

PROVIDER: S-EPMC2587137 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature