Prehypertension during young adulthood and coronary calcium later in life.

ABSTRACT:

Background

High blood pressure in middle age is a well-established risk factor for cardiovascular disease, but the consequences of low-level elevations during young adulthood are unknown.

Objective

To measure the association between prehypertension exposure before age 35 years and coronary calcium later in life.

Design

Prospective cohort study.

Setting

Four communities in the United States.

Participants

Black and white men and women age 18 to 30 years recruited for the CARDIA (Coronary Artery Risk Development in Young Adults) Study in 1985 through 1986 who were without hypertension before age 35 years.

Measurements

Blood pressure trajectories for each participant were estimated by using measurements from 7 examinations over the course of 20 years.

SUBMITTER: Pletcher MJ 

PROVIDER: S-EPMC2587255 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature