Real-time MR imaging-guided laser atrial septal puncture in swine.

ABSTRACT:

Purpose

The authors performed this study to report their initial preclinical experience with real-time magnetic resonance (MR) imaging-guided atrial septal puncture by using a MR imaging-conspicuous blunt laser catheter that perforates only when energized.

Materials and methods

The authors customized a 0.9-mm clinical excimer laser catheter with a receiver coil to impart MR imaging visibility at 1.5 T. Seven swine underwent laser transseptal puncture under real-time MR imaging. MR imaging signal-to-noise ratio profiles of the device were obtained in vitro. Tissue traversal force was tested with a calibrated meter. Position was corroborated with pressure measurements, oximetry, angiography, and necropsy. Intentional non-target perforation simulated serious complication.

Re

SUBMITTER: Elagha AA 

PROVIDER: S-EPMC2587284 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature