Left inferior frontal gyrus is critical for response inhibition.

ABSTRACT:

Background

Lesion studies in human and non-human primates have linked several different regions of prefrontal cortex (PFC) with the ability to inhibit inappropriate motor responses. However, recent functional neuroimaging studies have specifically implicated right inferior PFC in response inhibition. Right frontal dominance for inhibitory motor control has become a commonly accepted view, although support for this position has not been consistent. Particularly conspicuous is the lack of data on the importance of the homologous region in the left hemisphere. To investigate whether the left inferior frontal gyrus (IFG) is critical for response inhibition, we used neuropsychological methodology with carefully characterized brain lesions in neurological patients.

Results

Twelve

SUBMITTER: Swick D 

PROVIDER: S-EPMC2588614 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature