A molecular genetics laboratory course applying bioinformatics and cell biology in the context of original research.

ABSTRACT: Research based laboratory courses have been shown to stimulate student interest in science and to improve scientific skills. We describe here a project developed for a semester-long research-based laboratory course that accompanies a genetics lecture course. The project was designed to allow students to become familiar with the use of bioinformatics tools and molecular biology and genetic approaches while carrying out original research. Students were required to present their hypotheses, experiments, and results in a comprehensive lab report. The lab project concerned the yeast casein kinase 1 (CK1) protein kinase Yck2. CK1 protein kinases are present in all organisms and are well conserved in primary structure. These enzymes display sequence features that differ from other protein kinase

SUBMITTER: Brame CJ 

PROVIDER: S-EPMC2592051 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature