Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus.

ABSTRACT: Retapamulin MICs of > or =2 microg/ml were noted for 6 of 5,676 S. aureus recent clinical isolates evaluated. The ABC proteins VgaAv and VgaA were found to be responsible for the reduced susceptibility to pleuromutilins exhibited by these six isolates.

SUBMITTER: Gentry DR 

PROVIDER: S-EPMC2592886 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature