Asbestos-related pleural and lung fibrosis in patients with retroperitoneal fibrosis.

ABSTRACT:

Background

Retroperitoneal fibrosis (RPF) is a rare fibroinflammatory disease that leads to hydronephrosis and renal failure. In a case-control study, we have recently shown that asbestos exposure was the most important risk factor for RPF in the Finnish population. The aim of this study was to evaluate the relation of asbestos exposure to radiologically confirmed lung and pleural fibrosis among patients with RPF.

Methods

Chest high-resolution computed tomography (HRCT) was performed on 16 unexposed and 22 asbestos-exposed RPF patients and 18 asbestos-exposed controls. Parietal pleural plaques (PPP), diffuse pleural thickening (DPT) and parenchymal fibrosis were scored separately.

Results

Most of the asbestos-exposed RPF patients and half of the asbestos-exposed contr

SUBMITTER: Uibu T 

PROVIDER: S-EPMC2596089 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature