Cost-effectiveness of antiviral stockpiling and near-patient testing for potential influenza pandemic.

ABSTRACT: A decision analytical model was developed to investigate the cost-effectiveness of stockpiling antiviral (AV) drugs for a potential influenza pandemic in the United Kingdom and the possible role of near-patient testing in conserving AV drug stocks. Under base-case assumptions (including a fixed stockpile that was smaller than the clinical attack rate), the treat-only option (treating all symptomatic patients with AV drugs) would be considered cost-effective ( pound1,900- pound13,700 per quality-adjusted life year [QALY] gained, depending on the fatality scenario), compared with no intervention (nonintervention but management of cases as they arise). The test-treat option (testing all symptomatic patients but treating those with positive tests results only) would result in moderate gains in

SUBMITTER: Siddiqui MR 

PROVIDER: S-EPMC2600182 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature