Splenic rupture and malignant Mediterranean spotted fever.
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ABSTRACT:
SUBMITTER: Schmulewitz L
PROVIDER: S-EPMC2600289 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Publications
Splenic rupture and malignant Mediterranean spotted fever.
Schmulewitz Laura L Moumile Kaoutar K Patey-Mariaud de Serre Natacha N Poirée Sylvain S Gouin Edith E Mechaï Frédéric F Cocard Véronique V Mamzer-Bruneel Marie-France MF Abachin Eric E Berche Patrick P Lortholary Olivier O Lecuit Marc M
Emerging infectious diseases 20080601 6
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Project description:BackgroundSplenic rupture associated with trauma is common within the population, however, spontaneous splenic rupture is noted to be a rarity in clinical practice. Spontaneous splenic rupture is usually associated with hematologic, neoplastic, or infectious disorders, with infectious mononucleosis associated with Epstein-Barr virus being the most common cause worldwide. Spontaneous splenic rupture without underlying cause is thought to be exceedingly rare. In this article we present a case involving a true spontaneous splenic rupture.Case descriptionWe present the case of a 73-year-old female with past medical history significant for hypothyroidism, hypertension, squamous cell carcinoma of the chest, and history of tobacco use who presented to the emergency department with acute onset of left-sided flank pain radiating to her shoulder beginning three days prior. Computed tomography of the abdomen and pelvis without contrast revealed an acute splenic injury concerning for rupture with contour obscured by blood products with associated mild to moderate hemoperitoneum. The decision was made to proceed with emergent exploratory laparotomy and splenectomy. Patient received her post splenectomy vaccinations. On follow-up appointment, patient was noted to be doing well.ConclusionsThis case highlights the importance of early diagnosis and treatment of atraumatic splenic rupture, as delayed diagnosis and treatment is associated with significant morbidity and mortality. Operative intervention including splenectomy remains the mainstay of treatment, in addition to appropriate resuscitation. Some authors have reported cases in which hemodynamically stable patients are able to be treated non-operatively, however, the long-term consequences are unknown. Atraumatic spontaneous splenic rupture is often low on the differential diagnoses due to its rarity. Unfortunately, it carries a high risk of morbidity and mortality, and thus timely diagnosis and intervention is imperative.
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