Integrating host genomics with surveillance for invasive bacterial diseases.

ABSTRACT: We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to a newborn dried blood spot (nDBS) repository. Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neisseria meningitidis, and identified variants associated with susceptibility to this disease.

SUBMITTER: Crawford DC 

PROVIDER: S-EPMC2600343 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature