Mechanical tissue optical clearing devices: enhancement of light penetration in ex vivo porcine skin and adipose tissue.

ABSTRACT:

Background and objective

The complex morphological structure of tissue and associated variations in the indices of refraction of components therein, provides a highly scattering medium for visible and near-infrared wavelengths of light. Tissue optical clearing permits delivery of light deeper into tissue, potentially improving the capabilities of various light-based therapeutic techniques, such as adipose tissue removal or reshaping.

Study design/materials and methods

We report results of a study to evaluate effectiveness of novel mechanical tissue optical clearing devices (TOCD) using white light photography and infrared imaging radiometry (IIR). The TOCD consists of a pin array and vacuum pressure source applied directly to the skin surface. IIR images recorded light absor

SUBMITTER: Rylander CG 

PROVIDER: S-EPMC2605205 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature