Corpus callosal area differences and gender dimorphism in neuroleptic-naive, recent-onset schizophrenia and healthy control subjects.

ABSTRACT: The study of corpus callosal morphometry is important to unravel the underlying connectivity disturbance in schizophrenia. We studied the corpus callosal area in schizophrenia subjects compared to healthy subjects, while controlling for several confounders that could affect morphometric measures of the corpus callosum (CC). Areas of the whole CC and its sub-regions obtained by two geometric partitioning schemes were studied in 23 right-handed neuroleptic-naïve, recent-onset, schizophrenia patients and compared with 23 right-handed age-, sex- and education-matched healthy subjects. The patients did not differ from controls in whole CC area. On tripartite division of the CC, the area of the anterior sub-region was significantly higher in patients compared to controls. On radial division into

SUBMITTER: John JP 

PROVIDER: S-EPMC2605782 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature