Albuminuria and dementia in the elderly: a community study.

ABSTRACT:

Background

Dementia is associated with microvascular disease of the retina. In this study, we examine whether cognitive status (normal cognition, mild cognitive impairment, and dementia) is associated with albuminuria, a microvascular disorder of the kidney.

Study design

Cross-sectional analysis.

Setting & participants

2,316 participants from the Cardiovascular Health Cognition Study who underwent brain magnetic resonance imaging and testing for albuminuria.

Predictor

Doubling of albuminuria.

Outcome

Dementia defined according to neuropsychological and clinical evaluation.

Measurements

Multinomial logistic modeling was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) of dementia and mild cognitive impairment with doubling of a

SUBMITTER: Barzilay JI 

PROVIDER: S-EPMC2607238 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature