MOSAIC: an online database dedicated to the comparative genomics of bacterial strains at the intra-species level.

ABSTRACT:

Background

The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been developed to align complete genomes at the nucleotide level but their use and the biological interpretation of results are not straightforward. It is therefore necessary to develop new resources to access, analyze, and visualize genome comparisons.

Description

Here we present recent developments on MOSAIC, a generalist comparative bacterial genome database. This database provides the bacteriologist community with easy access to comparisons of complete bacterial genomes at the intra-species level. The strategy we developed for comparison allows us to define two types of regions in bacterial genomes:

SUBMITTER: Chiapello H 

PROVIDER: S-EPMC2607288 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature