Extended vs short-term buprenorphine-naloxone for treatment of opioid-addicted youth: a randomized trial.

ABSTRACT:

Context

The usual treatment for opioid-addicted youth is detoxification and counseling. Extended medication-assisted therapy may be more helpful.

Objective

To evaluate the efficacy of continuing buprenorphine-naloxone for 12 weeks vs detoxification for opioid-addicted youth.

Design, setting, and patients

Clinical trial at 6 community programs from July 2003 to December 2006 including 152 patients aged 15 to 21 years who were randomized to 12 weeks of buprenorphine-naloxone or a 14-day taper (detox).

Interventions

Patients in the 12-week buprenorphine-naloxone group were prescribed up to 24 mg per day for 9 weeks and then tapered to week 12; patients in the detox group were prescribed up to 14 mg per day and then tapered to day 14. All were offered weekly indivi

SUBMITTER: Woody GE 

PROVIDER: S-EPMC2610690 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature