Genome plasticity of Vibrio parahaemolyticus: microevolution of the 'pandemic group'.

ABSTRACT:

Background

Outbreak of V. parahaemolyticus infections occurred since 1996 was linked to a proposed clonal complex, the pandemic group. The whole genome sequence provides an unprecedented opportunity for dissecting genome plasticity and phylogeny of the populations of V. parahaemolyticus. In the present work, a whole-genome cDNA microarray was constructed to compare the genomic contents of a collection of 174 strains of V. parahaemolyticus.

Results

Genes that present variably in the genome accounted for about 22% of the whole gene pool on the genome. The phylogenetic analysis of microarray data generated a minimum spanning tree that depicted the phylogenetic structure of the 174 strains. Strains were assigned into five complexes (C1 to C5), and those in each complex were rela

SUBMITTER: Han H 

PROVIDER: S-EPMC2612023 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature