Pre-segmented 2-Step IMRT with subsequent direct machine parameter optimisation - a planning study.

ABSTRACT:

Background

Modern intensity modulated radiotherapy (IMRT) mostly uses iterative optimisation methods. The integration of machine parameters into the optimisation process of step and shoot leaf positions has been shown to be successful. For IMRT segmentation algorithms based on the analysis of the geometrical structure of the planning target volumes (PTV) and the organs at risk (OAR), the potential of such procedures has not yet been fully explored. In this work, 2-Step IMRT was combined with subsequent direct machine parameter optimisation (DMPO-Raysearch Laboratories, Sweden) to investigate this potential.

Methods

In a planning study DMPO on a commercial planning system was compared with manual primary 2-Step IMRT segment generation followed by DMPO optimisation. 15 clinica

SUBMITTER: Bratengeier K 

PROVIDER: S-EPMC2612672 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature