Ontology highlight
ABSTRACT:
SUBMITTER: Ghedin E
PROVIDER: S-EPMC2613796 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20070901 5845
Parasitic nematodes that cause elephantiasis and river blindness threaten hundreds of millions of people in the developing world. We have sequenced the approximately 90 megabase (Mb) genome of the human filarial parasite Brugia malayi and predict approximately 11,500 protein coding genes in 71 Mb of robustly assembled sequence. Comparative analysis with the free-living, model nematode Caenorhabditis elegans revealed that, despite these genes having maintained little conservation of local synteny ...[more]