Involvement of a phospholipase C in the hemolytic activity of a clinical strain of Pseudomonas fluorescens.

ABSTRACT:

Background

Pseudomonas fluorescens is a ubiquitous Gram-negative bacterium frequently encountered in hospitals as a contaminant of injectable material and surfaces. This psychrotrophic bacterium, commonly described as unable to grow at temperatures above 32 degrees C, is now considered non pathogenic. We studied a recently identified clinical strain of P. fluorescens biovar I, MFN1032, which is considered to cause human lung infection and can grow at 37 degrees C in laboratory conditions.

Results

We found that MFN1032 secreted extracellular factors with a lytic potential at least as high as that of MF37, a psychrotrophic strain of P. fluorescens or the mesophilic opportunistic pathogen, Pseudomonas aeruginosa PAO1. We demonstrated the direct, and indirect - through increases

SUBMITTER: Rossignol G 

PROVIDER: S-EPMC2613904 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature