A randomized trial of atropine vs patching for treatment of moderate amblyopia: follow-up at age 10 years.

ABSTRACT:

Objective

To determine the visual acuity outcome at age 10 years for children younger than 7 years when enrolled in a treatment trial for moderate amblyopia.

Methods

In a multicenter clinical trial, 419 children with amblyopia (visual acuity, 20/40-20/100) were randomized to patching or atropine eyedrops for 6 months. Two years after enrollment, a subgroup of 188 children entered long-term follow-up. Treatment after 6 months was at the discretion of the investigator; 89% of children were treated.

Main outcome measure

Visual acuity at age 10 years with the electronic Early Treatment Diabetic Retinopathy Study test.

Application to clinical practice

Patching and atropine eyedrops produce comparable improvement in visual acuity that is maintained through age 10 yea

SUBMITTER: Pediatric Eye Disease Investigator Group 

PROVIDER: S-EPMC2614351 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature